Application
Immunohistochemistry Analysis: 1 µg/mL from a representative lot detected APOBEC3G in human spleen tissue.
Detect APOBEC-3G using this rabbit polyclonal antibody, Anti-APOBEC3G Antibody validated for use in western blotting & IHC.
General description
DNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G) is a member of the cytidine and deoxycytidylate deaminase family. APOBEC3G is a multi-isoform member of the cytidine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates. Similar to TRIM5 alpha which targets incoming retroviral capsids, APOBEC3G plays an important role in cellular defense against retroviral infection. It is expressed in spleen, testes, ovary, peripheral blood leukocytes, and several tumor cell lines.
Immunogen
KLH-conjugated linear peptide corresponding to the N-terminus of human APOBEC3G.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Quality
Evaluated by Western Blotting/Peptide Inhibition Assay Analysis in Caco-2 cell lysate.
Western Blotting/Peptide Inhibition Assay Analysis: 5 µg/mL of this antibody detected APOBEC3G in 15 µg of Caco-2 cell lysate.
Specificity
This antibody recognizes the N-terminus of APOBEC3G.
Target description
~46 kDa observed
This product has met the following criteria to qualify for the following awards: