Cytokeratin 8 18 (B22.1 B2

General description

Cytokeratins 8 &18 (CK 8 & 18) are major components of the intermediate filaments in the thyroid, liver, and most simple epithelia (e.g. breast, gastrointestinal and respiratory tracts). Anti-CK 8 & 18 is found to stain most adenocarcinomas and squamous cell carcinomas. CK8 & 18 are frequently used as the epithelial markers for identifying Paget cells, metastatic gastric, and colorectal carcinomas.

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Linkage

Cytokeratin 8 & 18 Positive Control Slides, Product No. 818S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

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Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide

Preparation Note

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Quality