Application

C12-NBD ceramide is suitable for its use:as a substrate to measure the activity of acid, alkaline and neutral ceramidasesin in vitro ceramidase activity assayin ceramide phosphoethanolamine (CPE) synthase assay to determine the K_m and V_max of sphingomyelin synthase (SMS1, SMS2, and SMSr)

Biochem/physiol Actions

Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthase family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (810211C-1mg)