Application
12-NBD Stearate has been used in the fluorescent labeling of omega-3 fatty acid in biomaterial films and as a ligand for fatty acid binding protein 5 (FABP5) in competitive binding based high throughput fluorescence displacement assay. It may be used a ligand fluorescence displacement assay of fatty-acid binding protein 5 (FABP5).
Biochem/physiol Actions
12-NBD Stearate incorporated in lipid droplets and is used majorly in fluorescence displacement binding studies of fatty-acid binding proteins. The sterol carrier protein-2 (SCP-2) 15-kDa isoform favours NBD Stearate transport. The uptake of NBD Stearate is regulated by fatty acid binding protein (FABP) expression regulates uptake and inhibited by filipin III.
General description
12-NBD Stearate is amphipathic, nonesterifiable fluorescent fatty acid probe and is a long-chain fatty acid (LCFA) derivative.
Packaging
5 mL Amber Glass Screw Cap Vial (810110P-1mg)
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