3 BETA 24S-DIHYDROXY-5-CHOLESTENOIC ACID

Code: 700130P-1MG D2-231

Biochem/physiol Actions

Cholestenoic acid (CA) is a ligand to nuclear receptor. Based on the structural features, CA may elicit neurotoxic or neuroprotective effects. Defects...


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Biochem/physiol Actions

Cholestenoic acid (CA) is a ligand to nuclear receptor. Based on the structural features, CA may elicit neurotoxic or neuroprotective effects. Defects in the enzymes catalyzing the formation of cholestenoic acids are implicated in disorders related to motor neuron degeneration.

General description

3β,24S-dihydroxy-5-cholestenoic acid is a cholestenoic acid (CA). The enzyme sterol 27-hydroxylase (CYP27A1) catalyzes the synthesis of CA in the mitochondria.

Packaging

5 mL Amber Glass Screw Cap Vial (700130P-1mg)

assay>99% (TLC)
formpowder
manufacturer/tradenameAvanti Polar Lipids 700130P
packagingpkg of 1 × 1 mg (700130P-1mg)
shipped indry ice
SMILES stringO[C@H](C1)CC[C@](C1=CC2)(C)C3C2C(CC[C@@H]4[C@H](C)CC[C@H](O)[C@@H](C)C(O)=O)[C@]4(C)CC3
storage temp.−20°C
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