Biochem/physiol Actions

Primary TargetAMPA receptors

General description

A positive allosteric modulator selective for AMPA receptors. Slows down AMPA receptor deactivation rate without altering the agonist potency. A leading candidate of ampakine nootropic for cognitive enhancement. Widely used in studies in a variety of brain functions (i.e. learn and memory, cognition) and disorders (depression, anxiety disorder, Alzheimer′s disease, and aging).

A positive allosteric modulator selective for AMPA receptors. Slows down AMPA receptor deactivation rate without altering the agonist potency. A leading candidate of ampakine nootropic for cognitive enhancement. Widely used in studies in a variety of brain functions (i.e. learn and memory, cognition) and disorders (depression, anxiety disorder, Alzheimer′s disease, and aging).Please note that the molecular weight for this compound is batch-specific due to variable water content.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Koliaki, C., et al. 2012. CNS Neuroscience & Therapeutics.18, 302.Lynch, G., et al. 2011. Pharmacol. Biochem. Behav.99, 116.Nakamura, K., et al. 2001. Eur. J. Pharmacol.420, 33.Ito, I. et al., 1990. J. Physiol.424, 553.Isaacson et al., 1991. PNAS.88, 1093.

Packaging

50 mg in Glass bottle

Warning

Toxicity: Standard Handling (A)