IPTG; Hemidioxane Adduct

General description

A free flowing carbohydrate that induces expression of the lac operon of E. coli by allosterically interacting with the repressor molecule. Inducer of β-D-galactosidase.

A free-flowing, hygroscopic carbohydrate that induces expression of the lac operon of E. coli by allosterically interacting with the repressor molecule. Inducer of β-D-galactosidase. This preparation contains 15% dioxane.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Mathur, A., et al. 2000. Cardiovasc. Res. 46, 126.Chanda, B., and Mathew, M.K. 1999. Biochim Biophys. Acta 1416, 92.Dedov, V.N., and Roufogalis, B.D. 1999. FEBS Lett. 456, 171.Polla, B.S., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 6458.White, R.J., et al. 1996. J. Neurosci. 16, 5688.Ankacrona, M., et al. 1995. Neuron 15, 961.Reers, M., et al. 1995. Methods Enzymol. 260, 406.Ravanello, M.P., and Kruby, D.E. 1994. J. Virol.68, 6401.Schmitz, M.L., and Baeurerle, P.A. 1994. Biotechniques17, 714.Cossarizza, A., et al. 1993. Biochem. Biophys. Res. Commun. 197, 40.Lama, J., et al. 1992. Gene117, 185.Zhang, Y., and Moss, B. 1991. Proc. Natl. Acad. Sci. USA88, 1511.Rodriquez, J.F., and Smith, G.L. 1990. Nucleic Acids Res.18, 5347.Date, T., et al. 1988. Biochem. Biophys. Res. Commun.151, 598.Lee, S.G., et al. 1988. Biochemistry27, 2983.Cho, S., et al. 1985. Biochem. Biophys. Res. Commun.128, 1268.

Packaging

5 g in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Warning

Toxicity: Carcinogenic / Teratogenic (D)