TOBRAMYCIN UNITED STATES PHARMACOPEIA (

Code: 1667508-350MG D2-231

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseas...


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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

It is intended to be used as a USP reference standard in specified quality tests and assays.(1)Also used to prepare the standard solution for identification and assay of tobramycin and its different dosage forms using thin-layer chromatography (TLC) and liquid chromatography (LC) combined with UV detection at 365 nm respectively, as prescribed in the United States Pharmacopeia (USP) for the following monographs: Tobramycin Tobramycin for Injection Tobramycin Ophthalmic Ointment Tobramycin Ophthalmic Solution Tobramycin Injection Tobramycin Sulfate Tobramycin and Dexamethasone Ophthalmic Suspension Tobramycin Inhalation Solution Tobramycin and Fluorometholone Acetate Ophthalmic Suspension Tobramycin and Dexamethasone Ophthalmic Ointment

Biochem/physiol Actions

Tobramycin is an aminoglycoside. Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Spectrum of Activity: Gram negative bacteria. Not effective against Enterococci.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

USP issued SDS can be found here.

Sales restrictions may apply.

application(s)pharmaceutical (small molecule)
formatneat
gradepharmaceutical primary standard
InChI keyNLVFBUXFDBBNBW-SNGYORCQSA-N
InChI1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1
manufacturer/tradenameUSP
SMILES stringNC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O
storage temp.2-8°C
Cas Number32986-56-4
This product has met the following criteria to qualify for the following awards:



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