Application

Research Sub CategoryPI3K, Akt, & mTOR Signaling

Research CategorySignaling

Detect FIP200 using this Anti-FIP200 Antibody validated for use in WB.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Focal adhesion kinase family interacting protein of 200 kDa (FIP200) is a novel protein inhibitor for focal adhesion kinase (FAK). FIP200 inhibits kinase activity and associated cellular functions, such as cell adhesion, spreading, and motility in fibroblasts by binding directly to FAK.

Immunogen

Epitope: C-terminus

The immunogen was a synthetic peptide corresponding to the C-terminal region of FIP200.

Physical form

Unpurified rabbit serum in buffer containing 0.05% sodium azide.

Quality

Evaluated by western blot on HEK293 cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody was used to detect FIP200 in HEK293 cell lysate.

Specificity

This antibody recognizes the C-terminal region of FIP200.

Storage and Stability

Stable for 2 years at -20°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.

Target description

200 kDa