Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetModulator of noradrenergic activity

General description

Potent hypothalamic peptide neurotransmitter. An endogenous anti-psychotic compound that lowers blood pressure, increases vascular permeability, and increases plasma levels of glucagon, glucose, growth hormone and prolactin in rats. A modulator of noradrenergic activity. Heterogeneously distributed in the mammalian central nervous system and has many neurotransmitter-like characteristics.

Potent hypothalamic peptide neurotransmitter. Lowers blood pressure, increases vascular permeability and increases plasma levels of glucagon, glucose, growth hormone and prolactin in rats. A modulator of noradrenergic activity. Heterogeneously distributed in the mammalian central nervous system and has many neurotransmitter-like characteristics.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Kinkead, B., et al. 1999. Biol. Psychiatr.46, 340.Tyler, B.M., et al. 1998. Brain Res. 792, 246.Tsuda, K., and Masuyuma, Y. 1993. Am. J. Hypertens. 6, 473.

Packaging

Yes

Sequence

Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH

Warning

Toxicity: Standard Handling (A)