Corticotropin Releasing Factor

Code: 05-23-0050-1MG D2-231

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetAn immunomodulatory neuropeptide

Ge...


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€665.70 EACH
€818.81 inc. VAT

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetAn immunomodulatory neuropeptide

General description

An immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla. Functions by reducing hyperpolarizations. Acts as a functional antagonist of inflammatory mediators.

Releases ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla. Functions by reducing hyperpolarizations. Acts as a functional antagonist of inflammatory mediators.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Barmack, N.H., and Errico, P. 1993. J. Neurosci. 13, 4647.Wei, E.T., et al. 1993. Ciba Found. Symp. 172, 258.Smith, E.M., et al. 1986. Nature321, 881.Udelsman, R., et al. 1986. Nature319, 147.

Packaging

Yes

Physical form

Supplied as an acetate salt.

Reconstitution

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Sequence

H-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH₂

Warning

Toxicity: Standard Handling (A)

assay≥97% (HPLC)
colorwhite to off-white
formlyophilized solid
InChI keyVXFVFWFSJFSXHN-FAUHKOHMSA-N
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inambient
solubility5% NH4OH: 1 mg/mL (prepared with H?O)
storage conditiondesiccated (hygroscopic), OK to freeze
storage temp.−20°C
Cas Number86784-80-7
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