Oz Biosciences SqualVax Vegetal 10mL

SqualVax Vegetal is a phytosqualene-based oil-in-water emulsion similar to MF59.

OZ Biosciences SqualVax is an oil-in-water emulsion made of squalene droplets in a continuous aqueous phase. The new SqualVax Vegetal is similar to the renown SqualVax vaccine adjuvant, except that squalene sourced from animal origins has been advantageously replaced with phytosqualene (plant-derived) extracted from first choice European olive oil.

Originally, the largest squalene natural source was the liver oil of certain fish, especially deep-sea sharks, from which it derives its name. Shark-derived squalene has been supplying global market demands for years since its initial discovery. However, intensive fishing had a devastating impact on marine ecosystems and endangered the populations of squalene producing shark species.

The SqualVax Vegetal vaccine adjuvant offers the same outstanding features as its counterpart derived from animal origin, but at a much lesser ecological cost.

SqualVax Vegetal is fully biodegradable, which is an important advantage over alternative oils that have been used in emulsion adjuvants, like Freund’s adjuvant that contains mineral oil (paraffin oil) and has long term persistence in the organisms.