Biochem/physiol Actions

Lyso-sphingomyelin (Lyso SM) or sphingosylphosphorylcholine (SPC) serves as a multifunctional bioactive sphingolipid in cardiovascular system, immune system, central nervous system and skin. It has a potential to regulate cell proliferation, migration, differentiation, metabolism and apoptosis. Patients with pathological conditions such as atopic dermatitis, Niemann-Pick disease (NPD) and cancer show considerably higher levels of Lyso SM.

Lysosphingolipids serves as a marker for many sphingolipidoses. Sphingosylphosphorylcholine serves as a bioactive lipid in some tissues and immune system.

General description

Sphingosylphosphorylcholine is derived from sphingomyelin. It is known to be localized to plasma and also present in lipoproteins.

Lyso-sphingomyelin (Lyso SM)- d7, is a deuterated derivative of Lyso SM. Lyso SM is an amphiphilic lysophospholipid containing sphingoid backbone and a phosphorylcholine. It is a de-acylated form of sphingomyelin.

Packaging

5 mL Amber Glass Screw Cap Vial (860639P-5mg)

5 mL Amber Glass Screw Cap Vial (860639P-1mg)