Analysis Note

Color (visual): white to yellow to beigeAppearance of substance (visual): beadsLoading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.30 - 0.60 mmol/gSwelling Volume (in DMF): lot specific resultThe polymer matrix is copoly styrene - 1 % DVB 100 - 200 mesh

General description

Dnp NovaTag™ resin is an ideal tool for the synthesis of FRET peptide substrates based on the 7-methoxycoumarin (Mca) and 2,4-dintrophenyl (Dnp) fluorophore/quench pair. The resin pre-loaded with the Dnp quencher group can be used direcly in Fmoc SPPS. Following peptide assembly, the Mca group is coupled to the N-terminal N-amino group using Mca-OSu, or introduced to a side-chain of Lys using Fmoc-Lys(Mca)-OH, to give after TFA cleavage the desired FRET peptide substrate.

The product number for this product was previously 04-12-3903.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Legal Information

NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 04-12-3903