General description
A novel histidine derivative for Fmoc SPPS in which the π-imidazole nitrogen is blocked with the acid-labile MBom group, In contrast to Fmoc-His(Trt)-OH, coupling of this derivative is free from the risk of racemization, even under base-mediated coupling conditions. Methoxyamine should be added to the cleavage mixture to scsvenge liberated formaldehyde.
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
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