Biochem/physiol Actions

Isocitrate dehydrogenase (IDH) plays a major role in the Krebs cycle by catalyzing the oxidative decarboxylation of isocitrate. The oxidative decarboxylation of isocitrate generates α-ketoglutarate and NADPH. NADPH produced is essential for the production of fatty acids and cholesterol. This NADP-dependent molecules serves as homodimers.

Packaging

1 g in poly bottle

500 mg in poly bottle

Quality

Crude

Unit Definition

One unit will convert 1.0 µmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37°C.