General description
Non-Binding surface (NBS™) multiwell plates have a modified polymer surface (PS) which results in a non-ionic hydrophilic surface (polyethylene oxide-like), thereby minimizing bio-interaction and enhancing the signal-to-noise ratio. Results have demonstrated NBS′s ability to significantly reduce protein and nucleic acid binding to polymers (﹤2 ng/cm2; over 90% reduction of protein binding compare to PS & PP surface), maintain enzyme activity, and inhibit adhesion of a number of cell lines. These novel surface technologies for assay plates are ideal for homogeneous assays such as Scintillation Proximity Assay (SPA). In addition to a 20+ fold increase in signal-to-noise ratio, selected assays have also displayed improved sensitivity and specificity. The recommended working volume of up to 20 µL to 80 µL for 384 well plates.
Round well design with a solid black flat bottom. 2.8 mm distance between well bottoms to plate bottom. 50 µL total well volume, with recommended working volume of 5-40 µL. High base plate design is compatible with automation and for bar coding. Validated by Molecular Devices for the FLIPR reader. Outer wells aligned for proper viewing with FLIPR. Ideal for miniaturized 384 well fluorescent homogeneous assays. Nonbinding surface (NBS) is a Corning proprietary treatment technology used on polystyrene microplates to create a nonionic hydrophilic surface (polyethylene oxide-like) that minimizes molecular interactions.
Legal Information
NBS is a trademark of Corning, Inc.
Corning is a registered trademark of Corning, Inc.
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