Poly-L-ornithine hydrochloride, mol wt 15,000-30,000

Analysis Note

Molecular weight based on viscosity.

Application

Poly-L-ornithine hydrochloride has been used as a substrate analog of acetyl-poly-L-lysine to study substrate binding and catalysis of the NAD-dependent protein deacetylase Hst2. It has been used to bind alginate-polycation-alginate (APA) microcapsules.

Biochem/physiol Actions

Poly-L-ornithine is a polycationic synthetic amino acid polymer. It boosts nasal absorption of hydrophilic macromolecular drugs. Poly-L-ornithine is a specialized coating that acts as a charge modifier.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Packaging

50, 100, 500 mg in poly bottle

10 mg in glass bottle