Tetrabenazine, >=98% (HPLC), solid

Code: T2952-10MG D2-231

Application

Tetrabenazine has been used for dopamine uptake assays in mouse brain cells1. Tetrabenazine has also been used for non-specific binding assays in postn...


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€161.49 10MG
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Application

Tetrabenazine has been used for dopamine uptake assays in mouse brain cells1. Tetrabenazine has also been used for non-specific binding assays in postnuclear supernatants derived from PC-12 and CV-1 cells2.

Biochem/physiol Actions

Tetrabenazine is a reversible type 2 vesicular monoamine transporter (VMAT) inhibitor. It depletes dopamine stores.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

10, 50 mg in glass bottle

Preparation Note

Tetrabenazine is soluble in DMSO at a concentration that is greater than 10 mg/ml and is insoluble in water.

assay≥98% (HPLC)
formsolid
InChI keyMKJIEFSOBYUXJB-GDBMZVCRSA-N
InChI1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/m1/s1
originatorRoche
Quality Level100
SMILES stringCOc1cc2CCN3C[C@@H](CC(C)C)C(=O)CC3c2cc1OC
solubilityDMSO: >10 mg/mL, H2O: insoluble
storage temp.2-8°C
Cas Number58-46-8
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