Application
BMS-303141 has been used for inhibition of ATP citrate lyase in breast cancer cell lines.
Biochem/physiol Actions
BMS-303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS-303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 µM, and lowers plasma triglycerides in a murine hyperlipdemia model.
Packaging
5, 25 mg in glass bottle
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