SC 19220, >=98% (HPLC), solid

Code: S3065-10MG D2-231

Application

SC 19220 was used to study the role of prostaglandin E2 in oxygen-glucose deprivation-induced neurotoxicity and preconditioning-induced neuroprotection...


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€153.21 10MG
€188.45 inc. VAT
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Application

SC 19220 was used to study the role of prostaglandin E2 in oxygen-glucose deprivation-induced neurotoxicity and preconditioning-induced neuroprotection in rat cortical cultures.

Biochem/physiol Actions

SC 19220 is a competitive antagonist of prostaglandin E receptors. It competes with PGE2 in regulating vesicourethral motility and increases the bladder capacity of rats. It inhibits the contraction of smooth muscles in response to prostaglandins E2 and F2α. SC 19220 also inhibits the formation of osteoclasts induced by vitamin D3, parathyroid hormone, IL-11 and IL-6.

EP1 Prostanoid receptor antagonist

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite
formsolid
Gene Informationhuman ... PTGER1(5731)rat ... Ptger1(25637)
InChI keyKNURFLJTOUGOOQ-UHFFFAOYSA-N
InChI1S/C16H14ClN3O3/c1-10(21)18-19-16(22)20-9-11-4-2-3-5-14(11)23-15-7-6-12(17)8-13(15)20/h2-8H,9H2,1H3,(H,18,21)(H,19,22)
mp190-191 °C (lit.)
Quality Level100
SMILES stringCC(=O)NNC(=O)N1Cc2ccccc2Oc3ccc(Cl)cc13
solubilityDMSO: soluble 10 mg/mL, H2O: insoluble
Cas Number19395-87-0
This product has met the following criteria to qualify for the following awards:



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