PQ401, >=98% (HPLC), powder

Code: P0113-10MG D2-231

Application

PQ401 has been used as:an insulin growth factor-1 receptor (IGF-IR) inhibitor in H1299 cells to test its effect on migration suppressiona reference inhibitor in d...


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€214.29 10MG
€263.58 inc. VAT
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Application

PQ401 has been used as:an insulin growth factor-1 receptor (IGF-IR) inhibitor in H1299 cells to test its effect on migration suppressiona reference inhibitor in dose-response measurements studiesan IGF1R inhibitor in sirtuin 6 (SIRT6)-deficient cardiomyocytes to test its effect on hypertrophy inhibition

Biochem/physiol Actions

PQ401 is an insulin growth factor-1 receptor (IGF-1R) inhibitor.

PQ401, a diaryl urea compound that serves as an anti-glioma agent.

Features and Benefits

This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

10 mg in glass bottle

assay≥98% (HPLC)
colorwhite
formpowder
InChI keyYBLWOZUPHDKFOT-UHFFFAOYSA-N
InChI1S/C18H16ClN3O2/c1-11-9-15(13-5-3-4-6-14(13)20-11)21-18(23)22-16-10-12(19)7-8-17(16)24-2/h3-10H,1-2H3,(H2,20,21,22,23)
Quality Level100
SMILES stringCOc1ccc(Cl)cc1NC(=O)Nc2cc(C)nc3ccccc23
solubilityH2O: ﹤2 mg/mL, DMSO: >10 mg/mL
storage temp.2-8°C
Cas Number196868-63-0
This product has met the following criteria to qualify for the following awards:



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