Application
PQ401 has been used as:an insulin growth factor-1 receptor (IGF-IR) inhibitor in H1299 cells to test its effect on migration suppressiona reference inhibitor in dose-response measurements studiesan IGF1R inhibitor in sirtuin 6 (SIRT6)-deficient cardiomyocytes to test its effect on hypertrophy inhibition
Biochem/physiol Actions
PQ401 is an insulin growth factor-1 receptor (IGF-1R) inhibitor.
PQ401, a diaryl urea compound that serves as an anti-glioma agent.
Features and Benefits
This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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Packaging
10 mg in glass bottle
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