Ochratoxin A, from Petromyces albertensis, >=98% (HPLC)

Application

Ochratoxin A has been used as a mycotoxin: to test its effect on metabolism and hypoxia in human embryonic kidney (HEK293) cellsto test its cytotoxic effects in bovine mammary epithelial cellsas a standard for gamma radiation studies with food products and in cytotoxic studies using Hep G2 cells

Biochem/physiol Actions

Ochratoxin A (OTA), a renal toxin, is produced majorly by Aspergillus and Penicillium fungal species. It is immunotoxic, teratogenic myelotoxic, and mutagenic. It effectively interrupts the intestinal barrier functions. OTA displays a long elimination half-life and stimulates the major inflammatory cytokines release.

Ochratoxin A is a mycotoxin found in food that is nephrotoxic and carcinogenic in the kidney and induces differentiation in cloned renal cell lines. Increases endoplasmic reticulum ATP-dependent Ca²⁺ pump activity.

Packaging

1, 5, 25 mg in glass bottle