GW2974, >=98% (HPLC), solid

Code: G0668-50MG D2-231

Biochem/physiol Actions

Potent and selective dual inhibitor of EGFR (IC50 = 0.016 mM) and ErbB-2 receptor tyrosine kinase.

Features and Benefits

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Your Price
€239.13 50MG
€294.13 inc. VAT

Biochem/physiol Actions

Potent and selective dual inhibitor of EGFR (IC50 = 0.016 mM) and ErbB-2 receptor tyrosine kinase.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from GlaxoSmithKline

Packaging

50, 250 mg in glass bottle

assay≥98% (HPLC)
coloryellow
formsolid
Gene Informationhuman ... EGFR(1956), ERBB2(2064)
InChI keyDYYZXRCFCVDSKD-UHFFFAOYSA-N
InChI1S/C23H21N7/c1-29(2)22-11-19-20(13-24-22)25-15-26-23(19)28-18-8-9-21-17(10-18)12-27-30(21)14-16-6-4-3-5-7-16/h3-13,15H,14H2,1-2H3,(H,25,26,28)
originatorGlaxoSmithKline
Quality Level100
SMILES stringCN(C)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnc2cn1
solubilityDMSO: ≥20 mg/mL
Cas Number202272-68-2
This product has met the following criteria to qualify for the following awards:



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