CEP-701 hydrate, >=98% (HPLC)

Code: C7869-1MG D2-231

Application

CEP-701 hydrate has been used as a tyrosine kinase inhibitor:to study its effects on early growth response protein (EGR) genes and nerve growth factor (NGF) stimu...


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Your Price
€187.37 1MG
€230.47 inc. VAT

Application

CEP-701 hydrate has been used as a tyrosine kinase inhibitor:to study its effects on early growth response protein (EGR) genes and nerve growth factor (NGF) stimulation in human epithelial cellsas a supplement in reservoir solution for co-crystallization studies with human receptor-interactingprotein kinase4 (RIPK4)as an FMS-like tyrosine kinase 3 (FLT3) inhibitor-gold nanoparticle conjugate to study its effects on acute myeloid leukemia

Biochem/physiol Actions

CEP-701 hydrate, also known as Lestaurtinib, can repress Janus kinase 2/signal transducer and activator of transcription 5 (JAK2/STAT5) signaling by the specific inhibition of JAK2.

CEP-701 is a Flt-3 receptor tyrosine kinase inhibitor.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

1, 5 mg in glass bottle

assay≥98% (HPLC)
colorwhite
formpowder
InChI keyLPOQWFBZBJTLEO-GMEYHWBASA-N
InChI1S/C26H21N3O4.H2O/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28;/h2-9,18,30,32H,10-12H2,1H3,(H,27,31);1H2/t18-,25+,26+;/m1./s1
Quality Level100
SMILES stringO.C[C@]12O[C@H](C[C@]1(O)CO)n3c4ccccc4c5c6C(=O)NCc6c7c8ccccc8n2c7c35
solubilityDMSO: >10 mg/mL
storage temp.−20°C
Cas Number111358-88-4
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