BAPTA-AM, >=95% (HPLC)

Code: A1076-25MG D2-231

Application

BAPTA-AM has been used :to reduce the elevation of cleaved caspase-3to block cell death, inhibit ROS (reactive oxygen species) production and inhibit caspase-8 ac...


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€280.54 25MG
€345.06 inc. VAT
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Application

BAPTA-AM has been used :to reduce the elevation of cleaved caspase-3to block cell death, inhibit ROS (reactive oxygen species) production and inhibit caspase-8 activationto exclude the effect of changes in intracellular Ca2+ ([Ca2+]i) concentration during seizure inductionto eliminate the increase of [Ca2+]i induced by 6-hydroxydopamine (6-OHDA)

Biochem/physiol Actions

Selective chelator of intracellular Ca2+ stores.

General description

BAPTA-AM inhibits free radical-mediated toxicity, enhances apoptosis in non-neuronal cells and protects neurons from ischemic damage. It regulates ion channels and blocks neuronal Ca2+-activated K+channel currents. BAPTA-AM maintains intracellular Ca2+ homeostasis.

Linkage

Membrane-permeable form of BAPTA.

Packaging

25 mg in ampule

assay≥95% (HPLC)
formpowder
InChI keyYJIYWYAMZFVECX-UHFFFAOYSA-N
InChI1S/C34H40N2O18/c1-23(37)47-19-51-31(41)15-35(16-32(42)52-20-48-24(2)38)27-9-5-7-11-29(27)45-13-14-46-30-12-8-6-10-28(30)36(17-33(43)53-21-49-25(3)39)18-34(44)54-22-50-26(4)40/h5-12H,13-22H2,1-4H3
Quality Level200
SMILES stringCC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)c1ccccc1OCCOc2ccccc2N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O
storage temp.−20°C
Cas Number126150-97-8
This product has met the following criteria to qualify for the following awards:



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