ANTI-INTS1

Application

Anti-INTS1 antibody produced in rabbit is suitable for immunohistochemistry studies at a dilution of 1:25 - 1:100.

Biochem/physiol Actions

INTS1 (Integrator complex subunit 1), a large nuclear protein, involved in the processing of small nuclear RNA as a major component of the Integrator complex. During transcriptional regulation and in RNA processing, it directly binds to the C-terminal domain of the RNA polymerase II largest subunit. It has been reported that INTS1 is also involved in different cell support processes such as the formation of a scaffold for the assembly of integrator complex.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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Immunogen

Synthetic peptide corresponding to residues near the N terminal of human integrator complex subunit 1

Physical form

Rabbit IgG in pH7.3 PBS, 0.05% NaN₃, 50% Glycerol.

Specificity

The antibody detects endogenous levels of total INTS1 protein.