Biochem/physiol Actions

Rgs18 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Rgs18 binds to G(i) alpha-1, G(i) alpha-2, G(i) alpha-3 and G(q) alpha.

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Immunogen

Synthetic peptide directed towards the N terminal of human RGS18

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: AKEKRNRLSLLLQRPDFHGETQASRSALLAKETRVSPEEAVKWAESFDKL