Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

The epitope recognized by PLA0168 maps to a region between residue 2597 and 2647 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).

Other Notes

Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able act as a link between cell membrane receptors and intracellular signaling proteins. Defects in Filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development.

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide