CASPASE 9; MSX-100UG

Application

Research CategoryApoptosis & CancerMetabolism

Research Sub CategoryCaspasesEnzymes & Biochemistry

Western blot: 1:1000 Immunohistochemistry (frozen and paraffin): 1:500 - 1:1000

Optimal working dilutions must be determined by end user.

Anti-Caspase 9 Antibody, clone 2-23 is an antibody against Caspase 9 for use in IP, WB, IH(P).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Recombinant human caspase-9 prodomain

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 04-443

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Purified immunoglobulin by protein A. Liquid in PBS, pH 7.6, with 0.1% sodium azide.

Format: Purified

Specificity

Recognizes 46-48 kDa full-length procaspase-9, human recombinant caspase-9 and procaspase-9 from human cell lysates. Highly specific to caspase-9 and shows no cross-reaction with other caspase family members. Activation of procaspase-9 by Apaf-1 in the cytochrome c pathway requires proteolytic cleavage to generate active caspase-9. Once activated, capsase-9 initiates a caspase cascade involving the downstream executioner caspases 3, 6 and 7.

Storage and Stability

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.