Milli-Mark Anti-CD16-FITC

Analysis Note

ControlPBMCs

Application

Research Sub CategoryImmunoglobulins & Immunology

Detect CD16 using this Milli-Mark Anti-CD16-FITC Antibody, clone DJ130c validated for use in FC.

Research CategoryInflammation & Immunology

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

CD16 is a 50-70 kDa glycoprotein which occurs in two isoforms, CD16a and CD16b. CD16a is a transmembrane molecule expressed on about 90% of NK cells and also found on macrophages and subsets of monocytes and T cells. CD16b is glycosyl phosphatidyl inositol-anchored and is expressed on virtually all neutrophils (Tetteroo, 1987; Tamm, 1996). Anti-CD16, DJ130c, was included in the Fifth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD16 (Schmidt, 1995).

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Protein A purified

PurifiedMouseConjugate in buffer containing Tris-HCl Other

Quality

Evaluated by flow cytometry using human PBMCs

Specificity

Antibody recognizes Human CD16 antigen.

Storage and Stability

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Target description

50-70 kDa (Tetteroo, 1987; Tamm, 1996)