Analysis Note
A mix of Chondroitin Sulfate Proteoglycans from chick brain (Chemicon CC117) was purified by the unique density and size of this class of molecules. Neurocan is purified from this mix using an immobilized monoclonal antibody. The resulting neurocan is pure and has chondroitin sulfate attached. Removing the chondroitin sulfate with chondroitinase, results in core proteins are primarily the full-length 250 kD form and a little of smaller neurocan fragments.
Application
Inhibition of cell-cell adhesion, cell-ECM adhesion or cell migration at:
0.1 to 30 micrograms / mL.
ELISA Assay: 0.05 to 5 micrograms / mL
Optimal working concentrations must be determined by the end user.
Research Sub CategoryNeurodegenerative Diseases
Research CategoryNeuroscience
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Neurocan, chicken.
Product Source: Chicken Brain.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Physical form
Purified Neurocan in PBS. Contains no preservative.
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
This product has met the following criteria to qualify for the following awards: