Anti-SAPAP2

Analysis Note

ControlL1210 cell lysate

Application

This SAPAP2 antibody is validated for use in WB & IHC for the detection of the SAPAP2 protein.

Research CategoryNeuroscience

Immunohistochemistry Analysis: 5 µg/mL of this antibody from a representative lot detected SAPAP2 in human brain tissue.

Research Sub CategorySynapse & Synaptic Biology

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2).

Immunogen

KLH-conjugated linear peptide corresponding to human SAPAP2.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Purified rabbit polyclonal in buffer containing PBS and 0.02% sodium azide.

Antigen Affinity Purified

Quality

Evaluated by Western Blot in L1210 cell lysate.

Western Bloting Analysis: 1 µg/mL of this antibody detected SAPAP2 in 15 µg of L1210 cell lysate.

Specificity

At least three isoforms of SAPAP2 are known to exist. This SAPAP2 antibody will not cross-react with other SAPAP proteins.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~114 kDa observed. Uncharacterized bands may be observed.