STIM1; RBX-100UG

Analysis Note

ControlJurkat lysate.

Application

Research Sub CategoryIon Channels & Transporters

Research CategoryNeuroscience

Optimal working dilutions must be determined by the end user.

Anti-STIM1 Antibody is an antibody against STIM1 for use in WB.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

TRP (transient receptor potential)-related ion channels (TRPCs) have been postulated as candidates for forming both receptor-operated (ROCE) and capacitative Ca2+ entry channels across the plasma membrane. ER transmembrane protein STIM1 senses the depletion of Ca2+ from ER stores. Orai proteins, interacting with TRPCs, act as regulatory subunits that confers STIM1-mediated store depletion sensitivity to these channels and regulate Ca2+ influx through the plasma membrane.

Immunogen

Synthetic Linear Peptide

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Protein A purified

Purified in PBS with 0.05% NaN3

Format: Purified

Quality

Routinely evaluated in western blotting using Jurkat lysate.

Specificity

Catalogue No. AB9870 recognizes the C-Terminus of STIM1.

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Target description

80 kDa