Fmoc-Asn(Trt)-OH, >=97.0% (sum of enantiomers, HPLC)

Code: 47672-5G-F D2-231

Application

Fmoc-Asn(Trt)-OH has been used to synthesize peptides on cellulose membrane by SPOT method

General description

Fmoc-Asn(Trt)-OH has g...


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€59.90 5G
€73.68 inc. VAT

Application

Fmoc-Asn(Trt)-OH has been used to synthesize peptides on cellulose membrane by SPOT method

General description

Fmoc-Asn(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Asn [1, 2]. Coupling can be performed by standard procedures. The trityl group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp residues. When Asn(Trt) is the N-terminal residue, the reaction time may need to be extended to ensure complete deprotection [3].

Packaging

1 kg in poly bottle

5, 25, 100 g in poly bottle

application(s)peptide synthesis
assay≥97.0%
formpowder
functional groupFmoc
InChI keyKJYAFJQCGPUXJY-UMSFTDKQSA-N
InChI1S/C38H32N2O5/c41-35(40-38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28)24-34(36(42)43)39-37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33/h1-23,33-34H,24-25H2,(H,39,44)(H,40,41)(H,42,43)/t34-/m0/s1
mp201-204 °C (lit.)
optical activity[α]20/D −15.0±1°, c = 1% in methanol
Quality Level100
reaction suitabilityreaction type: Fmoc solid-phase peptide synthesis
SMILES stringOC(=O)[C@H](CC(=O)NC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46
storage temp.2-8°C
Cas Number132388-59-1
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