CAPSAICIN EUROPEAN PHARMACOPOEIA (EP) R

Code: Y0000671 D2-231

Biochem/physiol Actions

Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P...


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Biochem/physiol Actions

Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.

Caution

Please find SDS provided by EDQM here..

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

agencyEP Reference Standard
application(s)pharmaceutical (small molecule)
formatneat
Gene Informationhuman ... TRPV1(7442)
gradepharmaceutical primary standard
InChI keyYKPUWZUDDOIDPM-SOFGYWHQSA-N
InChI1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
manufacturer/tradenameEDQM
mp62-65 °C (lit.)
SMILES stringCOc1cc(CNC(=O)CCCCC=CC(C)C)ccc1O
storage temp.2-8°C
Cas Number404-86-4
Hazard Class6.1
Un Number1544
Pack GroupIII
This product has met the following criteria to qualify for the following awards:



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