The new guidelines set by the United States Pharmacopeia (USP) have pushed the pharmaceutical and nutraceutical industries to provide accurate, quantifiable results for metal analysis in drugs, pharmaceutical substances and raw materials.

USP <232> outlines new limits in pharmaceutical products for arsenic, cadmium, lead, and mercury. ICP-MS instrumentation, along with accurate ICP-MS standards, allow for increased efficiency and accuracy of the analysis necessary to comply with the new regulations.

Use these standards can be used as a calibration or check standard to verify Oral Daily Dose PDE, Parenteral Component Limit or Parenteral Daily Dose PDE as well as Inhalation Component Limit or Daily Dose.

Chemicals sold by Cole-Parmer are not intended for and should not be (i) used for medical, surgical or other patient oriented applications, or (ii) combined with any food product or ingested in any form.

This multi-component standard contains 7 components.

• USP <232> Revision 40, Parenteral Mix 3 elemental impurities standard is a 125 mL bottle which contains 1,500 mg/kg (1,500 ppm) Molybdenum; 1,100 mg/kg (1,100 ppm) Chromium; 700 mg/kg (700 ppm) Barium; 600 mg/kg (600 ppm) Tin; 300 mg/kg (300 ppm) Copper; 250 mg/kg (250 ppm) Lithium; and 90 mg/kg (90 ppm) Antimony in 5% HNO3/tr. Tartaric Acid/tr. HF.

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