URB597, >=98% (HPLC), powder

Biochem/physiol Actions

Potent, selective fatty acid amide hydrolase (FAAH) inhibitor.

General description

URB597 binds to active sites of fatty acid amide hydrolases and inhibits their activity. URB597 alters expression of tyrosine hydroxylase and interacts with abnormal-cannabidiol (Abn-CBD) and peroxisome proliferator-activated receptors (PPARs). URB597 elicits antinociception property via cannabinoid receptor by maintaining endocannabinoid anandamide (AEA) levels. URB597 reduces abnormal hyperactivity in neurons and could be for treatment of seizures and improving synaptic plasticity.

Packaging

5, 25 mg in glass bottle

Preparation Note

URB597 is soluble in DMSO at a concentration that is approximately 14 mg/ml.