T0901317

Code: T2320-10MG D2-231

Application

T0901317 has been used in LXR agonist study in order to observe the expression of all dietary cholesterol-regulated genes in mice. It has also been used to stimul...


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€134.00 10MG
€164.82 inc. VAT
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Application

T0901317 has been used in LXR agonist study in order to observe the expression of all dietary cholesterol-regulated genes in mice. It has also been used to stimulate the radiolabeled peritoneal macrophages from WT (wildtype) and Tg (transgenic) mice for cellular cholesterol efflux assay.

Biochem/physiol Actions

T0901317 can prevent the secretion of insulin by acting on the metabolism of mitochondria.

LXR agonist whose treatment results in an LXR-dependent up-regulation of ABC1 gene expression

assay≥98%
Gene Informationhuman ... ABCA1(19), NR1H2(7376), NR1H3(10062)
InChI keySGIWFELWJPNFDH-UHFFFAOYSA-N
InChI1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2
mol wt481.3
Quality Level200
SMILES stringOC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c2ccccc2)(C(F)(F)F)C(F)(F)F
storage temp.−20°C
Cas Number293754-55-9
This product has met the following criteria to qualify for the following awards:



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