Tyrphostin A9, solid

Code: T182-5MG D2-231

Application

Tyrphostin A9 can be used for inhibiting tyrosine kinase functions in C2C12 cells. It has also been used to disrupt membrane potential in mammalian cells.

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€128.40 5MG
€157.93 inc. VAT
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Application

Tyrphostin A9 can be used for inhibiting tyrosine kinase functions in C2C12 cells. It has also been used to disrupt membrane potential in mammalian cells.

Biochem/physiol Actions

Tyrphostin A9 is a PDGF receptor tyrosine kinase inhibitor that can induce apoptosis in cancer cells, inhibit the growth of vascular smooth cells and block calcium release-dependent phosphorylations.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5 mg in glass bottle

25 mg in poly bottle

Preparation Note

Tyrphostin A9 is soluble in ethanol at 20 mg/ml, in DMSO at a concentration less than 25 mg/ml. It is insoluble in water.

assay≥98% (HPLC)
biological sourcesynthetic (organic)
coloryellow
formsolid
Gene Informationhuman ... EGFR(1956), ORAI1(84876), PDGFRA(5156), PDGFRB(5159)mouse ... Eef2k(13631), Prkaca(18747), Prkca(18750), Src(20779)
InChI keyMZOPWQKISXCCTP-UHFFFAOYSA-N
InChI1S/C18H22N2O/c1-17(2,3)14-8-12(7-13(10-19)11-20)9-15(16(14)21)18(4,5)6/h7-9,21H,1-6H3
mp139-140 °C
Quality Level100
SMILES stringCC(C)(C)c1cc(C=C(C#N)C#N)cc(c1O)C(C)(C)C
solubilityDMSO: ﹤25 mg/mL, ethanol: 20 mg/mL, H2O: insoluble
Cas Number10537-47-0
Hazard Class6.1
Un Number2811
Pack GroupIII
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