HPA-12

Code: SML2894-5MG D2-231

Biochem/physiol Actions

(1R,3S)-HPA-12 is a ceramide (Cer) analog that acts as a Cer transporter (CERT) antagonist and selectively inhibits cellular Cer conversion to sphingo...


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Biochem/physiol Actions

(1R,3S)-HPA-12 is a ceramide (Cer) analog that acts as a Cer transporter (CERT) antagonist and selectively inhibits cellular Cer conversion to sphingomyelin (SM), but not to glucosylceramide, by blocking CERT-mediated Cer ER-to-Golgi transport. Common culture dosing range: 1-10 µM.

assay≥98% (HPLC)
colorwhite to beige
formpowder
Quality Level100
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
Cas Number383418-30-2
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