SGC-CAMKK2-1

Code: SML2834-25MG D2-231

Biochem/physiol Actions

SGC-CAMKK2-1 (YL-36) is a potent and selective CaM kinase kinase (CaMKK) inhibitor (CAMKK2 IC50 = 30 nM) that inhibits C4-2 cellular AMPK p...


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Biochem/physiol Actions

SGC-CAMKK2-1 (YL-36) is a potent and selective CaM kinase kinase (CaMKK) inhibitor (CAMKK2 IC50 = 30 nM) that inhibits C4-2 cellular AMPK phosphorylation (IC50 = 1.6 µM) with selective affinity toward CAMKK1/2 over other kinases (404-kinase panel kinome-wide Discoverx screen).

assay≥98% (HPLC)
colorwhite to beige
formpowder
Quality Level100
SMILES stringCC1=CC(C2=CN=C(OC=C3C4=CC(C5CCCC5)=C(C(O)=O)C=C4)C3=C2)=CC=C1
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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