AQ1 TRIFLUOROACETIC ACID SALT

Code: SML2587-5MG D2-231

Biochem/physiol Actions

AQ1, an anthraquinone derivative, is a potent stabilizer of c-KIT G-quadruplexes (G4) that downregulates c-KIT mRNA and protein expression in human an...


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€76.40 5MG
€93.97 inc. VAT
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Biochem/physiol Actions

AQ1, an anthraquinone derivative, is a potent stabilizer of c-KIT G-quadruplexes (G4) that downregulates c-KIT mRNA and protein expression in human and canine cell lines. Also, AQ1 causes inhibition BCL2 gene expression in HGC27 and MCF7 cells. AQ1 inhibits proliferation of in varies human tumor cell lines including HCG27, MCF7 and imatinib resistant HMC1.2 cells.

assay≥98% (HPLC)
colorfaint yellow to dark orange
formpowder
solubilityH2O: 2 mg/mL, clear
storage temp.−20°C
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