NSC49652

Code: SML2544-5MG D2-231

Biochem/physiol Actions

NSC49652 is a orally active, potent and selective inhibitor of death receptor p75NTR (p75 neurotrophin receptor) that targets the interfaces between t...


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€93.20 5MG
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Biochem/physiol Actions

NSC49652 is a orally active, potent and selective inhibitor of death receptor p75NTR (p75 neurotrophin receptor) that targets the interfaces between transmembrane domains (TMDs). NSC49652 induces profound conformational changes and triggers p75NTR dependent cancer cell death. It inhibits the growth of cancer in melanoma mouse model.

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringOC1=CC=CC=C1C(/C=C/C2=CN=CC=C2)=O
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
Cas Number908563-68-8
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