NSAH

Code: SML2537-5MG D2-231

Biochem/physiol Actions

NSAH is a cell penetrant, potent and selective nonnucleoside reversible inhibitor of large subunit (hRRM1) of hRR (human ribonucleotide reductase). NS...


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Biochem/physiol Actions

NSAH is a cell penetrant, potent and selective nonnucleoside reversible inhibitor of large subunit (hRRM1) of hRR (human ribonucleotide reductase). NSAH binds to catalytic site of hRRM1. It inhibits hRR in cells. NSAH exhibit potent cytotoxicity toward cancer cells, while demonstrated very moderate toxicity against normal blood progenitor cells.

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringOC1=CC=CC=C1C(N/N=C/C2=C(C=CC=C3)C3=CC=C2O)=O
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
Cas Number1099592-35-4
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