NANCHANGMYCIN

Code: SML2251-5MG D2-231

Biochem/physiol Actions

Nanchangmycin is a broad spectrum polyether antibiotic recently shown to inhibit Zika virus entry. Nanchangmycin was found to potently inhibit entry i...


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€141.90 5MG
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Biochem/physiol Actions

Nanchangmycin is a broad spectrum polyether antibiotic recently shown to inhibit Zika virus entry. Nanchangmycin was found to potently inhibit entry in three distinct cell types including human brain microvascular endothelial cells (HBMECs) with two different strains of Zika virus. It was also found effective against other viruses such as West Nile, dengue, and chikungunya.

assay≥98% (HPLC)
biological sourceStreptomyces nanchangensis
colorwhite to beige
formpowder
InChI keyFELYAZAWTURXNF-JJIBRWJFSA-N
InChI1S/C47H78O14/c1-24(40(50)25(2)18-28(5)43(51)52)17-26(3)41-31(8)34(49)22-45(59-41)16-15-44(11,61-45)38-21-36(56-39-14-13-35(54-12)33(10)55-39)32(9)47(58-38)30(7)20-37(57-47)42-27(4)19-29(6)46(53,23-48)60-42/h17,25-39,41-42,48-49,53H,13-16,18-23H2,1-12H3,(H,51,52)/b24-17+
SMILES stringOC([C@@H](C)C[C@@H](C)C(/C(C)=C/[C@H](C)[C@]1([H])[C@H](C)[C@@H](O)C[C@]2(CC[C@]([C@@]3([H])C[C@H](O[C@@]4([H])O[C@H](C)[C@@H](OC)CC4)[C@@H](C)[C@@]5(O[C@]([C@@]6([H])O[C@@](O)(CO)[C@H](C)C[C@@H]6C)([H])C[C@@H]5C)O3)(C)O2)O1)=O)=O
solubilityDMSO: 2 mg/mL, clear
storage temp.−20°C
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