Biochem/physiol Actions

FM-479 is an FM-381 structural analog that exhibits no inhibitory potency against JAK3 or other kinases when used at the FM-381 effective dosing range of 100-300 nM. For characterization details of the active probe, FM-381, please visit the FM-381 probe summary on the Structural Genomics Consortium (SGC) website.FM-381, the active probe, is available from Sigma. To learn more about and purchase FM-381, click here.To learn about other SGC chemical probes, visit sigma.com/sgc

Features and Benefits

FM-479 is a negative control for FM-381, a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC