CBLC000 TRIFLUOROACETATE

Code: SML1974-5MG D2-231

Biochem/physiol Actions

CBLC000 is a potent inhibitor of FACT (facilitates chromatin transcription) complex that activates p53 and suppresses NF-kB without genotoxicity. CBLC...


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€88.93 5MG
€109.38 inc. VAT

Biochem/physiol Actions

CBLC000 is a potent inhibitor of FACT (facilitates chromatin transcription) complex that activates p53 and suppresses NF-kB without genotoxicity. CBLC000 induces chromatin trapping of FACT both in vitro and in vivo. CBLC000 exhibits brad anticancer activity. CBLC000 analog clinical candidate CBL0137 decreases self-renewal of GBM stem cells (GSC).

assay≥95% (HPLC)
colorwhite to beige
formpowder
SMILES stringCCN(CC)CCN1C2=C(C=C([N+]([O-])=O)C=C2)C3=C1C=CC([N+]([O-])=O)=C3.FC(F)(C(O)=O)F
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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