Biochem/physiol Actions

Otilonium bromide has the capability to prevent L-type Ca²⁺ channels and colonic contractile activity. It is a tolerable drug as it is absorbed poorly and has very less side effects.

Otilonium Bromide is a muscarinic receptor antagonist (antimuscarinic). Otilonium Bromide is a quaternary ammonium salt that exerts spasmolytic action selective on the distal gastrointestinal tract. It is used world-wide for the treatment of irritable bowel syndrome (IBS).

General description

Otilonium bromide is an antispasmodic. It contains a red color ACh (acetylcholine) like moiety bound to an aromatic system that ends with an octyl ether.

Packaging

5, 25 mg in glass bottle