HAMNO

Code: SML1234-5MG D2-231

Biochem/physiol Actions

HAMNO is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response. HAMNO...


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€133.60 5MG
€164.33 inc. VAT
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Biochem/physiol Actions

HAMNO is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response. HAMNO binds the N-terminal domain of RPA70 and inhibits both ATR autophosphorylation and phosphorylation of RPA32 Ser33 by ATR. HAMNO enhances DNA replication stress in cancer cells and slow tumor growth in vivo.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
coloryellow to orange
formpowder
Quality Level100
solubilityDMSO: 10 mg/mL, clear
storage temp.2-8°C
Cas Number138736-73-9
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